David Begley, UK



David J. Begley PhD is Senior Visiting Research Fellow at Kings College London, UK. He received his BSc (1967 Zoology) and his PhD (1971) from the University of Nottingham. His laboratory is part of the Drug Delivery Group in the Pharmaceutical Sciences Division at Kings College, investigating the blood-brain barrier, in particular, drug delivery to the central nervous system (CNS) with a special emphasis on lysosomal storage disorders and other inherited neurometabolic diseases. He is author of a significant number of key peer-reviewed papers on blood-brain barrier (BBB) function and drug delivery to the CNS and has contributed more than sixteen chapters on blood-brain barrier and CNS drug delivery to edited volumes. Dr Begley was the Friedrich Mertz Stiftungsgastprofessor, Johann Wolfgang Goethe-Universität, Frankfurt, for the academic year 1997-1998, which was awarded shortly after his collaboration with Prof. Jörg Kreuter initiated, at the Institute of Pharmaceutical Technology in Frankfurt. He remains visiting Docent at Goethe University. He took a sabbatical year at GlaxoSmithKline followed by a position as visiting Academic in Residence, during 2005 to 2007. He was Organiser and Chairman of the second Gordon Conference on “Barriers of the CNS” held in New Hampshire in 2002. He lectures frequently worldwide on the BBB and related topics and continues to receive research support from National Research Councils, the Pharmaceutical Industry, The European Union and Charitable Foundations. He founded in 2006, with Prof. Maurizio Scarpa of the University of Padua, Italy, “The Brains for Brain Research Foundation” a European Task Force, composed of clinicians, scientists, family associations and Pharma, dedicated to the study and improving treatment of neurodegenerative lysosomal storage and related diseases. The Foundation celebrated its 13th Annual Symposium in 2019 and has raised in excess of 3.5M€ to foster the charities aims. He jointly received, (with Kreuter), the Journal of Controlled Release award for “The Outstanding Paper of the Year” 2009 (J. Contr. Rel. 2009 137:78-86). He is currently continuing research into Lysosomal Storage Disorders and related diseases and their treatment. (www.brains4brain.eu).